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| Education | : | 1996.10-2000.1 Dr. rer. nat. (Ph.D. in Biophysics) Institute of Physics University of Duisburg Germany 1990.9-1992.6 M.Sc. Graduate Institute of Physics, National Taiwan University 1986.10-1990.6 Department of Physics, National Taiwan University |
| Experience | : | 2000.9-2002.-8 Bioinformatics Specialist, Howard Hughes Medical Institute, University of California at San Diego, U.S.A. 2000.1-2000.9 Postdoctoral Research Associate, John von Neuman Institute for Computing, Forschungszentrum Juelich, Germany 2002.9-2002.11 Visiting Scholar, Institute for Bioinformation Processing-2, Forschungszentrum Juelich, Germany 2002.12-2003.1 Visiting Scholar, Computing Centre, Academia Sinica 1993.2-1994.5 System and Database Administrator, Information Center, Army Headquarter, R.O.C. 1994.8-1996.7 Lab Teaching Assistant, Department of Physics, National Taiwan University |
| Honor | : | Who's Who in Science and Engineering 2006 |
| Research Areas | : | Statistical mechanics of biological macromoleculese |
| Lab Focus | : | My research area focuses on statistical mechanics of biological macromoleculese. e.g, proteins, nucleic acids, membranes, and drugs. A major effort has been on the development and application of computer models and simulation methods for molecular systems. Particular research problems include study of atomic mobility in proteins and membranes by molecular dynamics and Monte Carlo computer simulations; quantitative modeling of recognition and binding in ligand-receptor systems with solvation effects; development of methods for computing free energy change efficiently in solution phase processes; calculation of diffusion constants and diffusion encounter rates of rigid and flexible molecules in solution and onto biomembranes by Brownian dynamics simulations; modeling of subcellular and cellular processes, including signal transduction, gene expression, and cytoskeletal dynamics. |